The Penguins (7-3-0) won seven of eight to start the season, but they've dropped two straight after falling 4-3 to the New York Islanders on Friday. They haven't lost three consecutive regular-season contests since a six-game skid from Dec. 29, 2011-Jan. 11, 2012.
''We had some chances to build on our lead, and we didn't,'' Crosby said. ''We made some mistakes and they made us pay.''
The captain had his career-best eight-game point streak to start a season snapped in Monday's 1-0 loss to Colorado, but he scored his eighth goal in the second period Friday and also has 10 assists to lead the league in points.
Crosby has 11 goals and four assists during a nine-game point streak against the Leafs, scoring a goal in eight straight before finishing with two assists in the most recent matchup - a 3-1 win March 14.
He has nine goals and eight assists in 12 career road matchups against Toronto, which has lost three of four after falling 5-2 in Columbus on Friday. The Maple Leafs (7-3-0) won six of their first seven prior to this stretch.
Toronto's lone victory during the slump came Tuesday, as Kessel recorded his fourth career hat trick in a 4-2 win over Anaheim. Kessel scored 40 seconds into the second period Friday before the Blue Jackets pulled away.
Kessel, who has a team-best 12 points, briefly left the bench later in the period but returned to start the third. The reason for his departure wasn't immediately clear.
Jonathan Bernier made 31 saves, but it's likely James Reimer will be in net for the second of a back-to-back. Reimer is 2-0-0 but also has been pulled in two starts while posting a 3.17 goals-against average. He's 3-0-2 with a 2.51 GAA in five career starts against Pittsburgh.
The Leafs played Friday without Joffrey Lupul, who is tied with Kessel for the team lead with six goals, after he suffered a bone bruise due to being hit with a puck in practice Thursday. It's unclear if he'll be able to play against the Penguins.
David Clarkson, though, made his team debut following a 10-game suspension for leaving the bench to join a fight during a preseason game against Buffalo.
''It's all about winning now,'' Clarkson said. ''It doesn't matter how anyone feels. We have to find a way to win, and to be better than that.''
Pittsburgh got defenseman Kris Letang back Friday after he missed the first nine games with a lower-body injury. He played more than 25 minutes in front of Jeff Zatkoff, who made 21 saves.
"I felt pretty good," Letang said. "I mean, a couple mistakes here and there. But (it's) something (where) I need to get back into it and making sure I make good decisions."
Marc-Andre Fleury, who is 7-1-0 with a 1.74 GAA, will be back in net Saturday. He's 5-1-1 despite a 3.31 GAA and .876 save percentage in his last seven starts against Toronto.
Penguins winger Matt D'Agostini (lower-body injury) is eligible to come off injured reserve and could make his season debut.
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