The teams will meet Saturday night at Gillette Stadium.
The matchup was determined when third-seeded Cincinnati lost to San Diego 27-10 on Sunday, one day after fourth-seeded Indianapolis (12-5) beat Kansas City 45-44 as Luck threw four touchdown passes and the Colts rallied from a 28-point deficit.
Second-seeded New England (12-4) had a first-round bye for the fourth straight season.
In the previous playoff meeting between the teams, the Colts won the AFC championship game 38-34 after trailing the Patriots 21-6 at halftime seven years ago.
New England goes into Saturday's game with five wins in six games. Indianapolis has won its past four.
AP NFL website: www.pro32.ap.org
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