Cobb broke his fibula against the Baltimore Ravens during a 19-17 win.
He's not allowed to practice for six weeks.
Reserve offensive lineman Greg Van Roten was placed on injured reserve with a foot injury.
The Packers are also dealing with a sprained knee for wide receiver James Jones.
The Packers signed linebacker Victor Aiyewa to the practice squad.
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Aaron Wilson covers the Ravens for The Baltimore Sun.Follow @footballpost on Twitter for the latest news
This story originally appeared on Nationalfootballpost.com
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