Denver Broncos quarterback Peyton Manning and his wife, Ashley, will donate $500,000 to the Pat Summitt Foundation.
The foundation was founded in November 2011 to help fight Alzheimer's disease. Summitt, the longtime head coach for the Lady Volunteers, announced in August 2011 that she had been diagnosed with Alzheimer's. She stepped down last April.
Patrick Wade, the foundation's director, said in a statement that the Mannings' gift is the largest gift announcement made to Summitt's foundation.
The foundation advances research for a cure for Alzheimer's, provides support services for patients and caregivers, and is involved in education and public awareness campaigns.
Summitt went 1,098-208 and won eight national titles in 38 seasons at Tennessee. She remains on staff as head coach emeritus.
Manning, who played for the Volunteers from 1994-1997, serves on the Foundation's Advisory Board's honorary co-chairs.