The Liga giant has not dropped points on its own turf since drawing 1-1 with Espanyol last December and will be confident of recording another victory against a side it has put four goals past in each of their last three home meetings.
Cristiano Ronaldo scored seven goals in those three games, with the Portuguese superstar boasting an overall record of 11 goals in seven appearances against Luis Garcia’s men since joining the Blancos in 2009.
Carlo Ancelotti’s side goes into the encounter with 10 points from its four Liga games so far this season and on the back of an entertaining 2-2 draw at newly promoted Villarreal last weekend.
That match saw world-record signing Gareth Bale’s first appearance for Madrid, and the Welshman marked the occasion with a goal.
Ronaldo was also on the score sheet at El Madrigal, and looks poised to continue his remarkable record against Getafe after following that goal up with a hat trick in Real’s 6-1 Champions League demolition of Galatasaray on Tuesday.
Bale is in line to make his first start for the club after coming on as a substitute at the Turk Telecom Arena, although goalkeeper Iker Casillas looks set to miss out after suffering a rib injury in Istanbul.
Marcelo (thigh) and Raphael Varane (knee) are doubtful, while Ancelotti will definitely be without long-term absentee Xabi Alonso (foot), although Fabio Coentrao may be available after recovering from a muscle problem.
Getafe makes the trip across Madrid after securing its first Liga victory of the season against Osasuna last time out and can also take heart from the fact it came from behind to defeat Madrid 2-1 at home last term.
However, Garcia’s side has lost its last six top-flight away games and have won just once in the nine games it has played at the Bernabeu - a 1-0 success in Feb. 2008.
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