Reilly Smith had a power-play and an empty-netter for Boston, which won its seventh straight at home. The Bruins haven't lost there in regulation since late October, going 12-0-2 in their last 14 games.
Zemgus Girgensons scored for the Sabres, who beat the Bruins 4-2 in Buffalo on Thursday night. The Sabres, who haven't won three straight this season, had a two-game winning streak broken.
Tuukka Rask, who was rested Thursday, made 34 saves, including a pair of key stops early in the third period.
Buffalo backup Jhonas Enroth stopped 35 shots and dropped to 1-7-3.
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