VALENCIA, Spain (AP) -- John Isner of the United States edged Ernests Gulbis of Latvia 7-6 (4), 7-6 (2) on Wednesday at the Valencia Open.
Top-seeded David Ferrer reached the second round by beating Gael Monfils of France 6-3, 6-2. Monfils appeared to be in pain during the second set, but kept playing.
Philipp Kohlschreiber upset fellow German Tommy Haas, who was seeded second, 3-6, 6-3, 6-3.
Fabio Fognini also advanced by topping Spaniard Marcel Granollers 6-3, 6-2. Jeremy Chardy beat Florian Mayer 4-6, 7-5, 6-3, and Jarkko Nieminen defeated Benoir Paire 6-3, 6-3.
Jeremy Chardy of France came from a set down to beat Florian Mayer of Germany 4-6, 7-5, 6-3 in a late match.
Other winners included fifth-seeded Jerzy Janowicz of Poland, who will next face Ferrer, Mikhail Youzhny of Russia and third-seeded Nicolas Almagro of Spain.