Everton eked by Juventus in a penalty shootout to advance in the winners' bracket. U.S. goalkeeper Tim Howard made a clutch save, and 19-year-old defender John Stones converted a cheeky chip in the shootout to boost the Toffees past the Italian champion.
Real Madrid had a considerably easier first-round matchup, coasting by a shorthanded LA Galaxy side 3-1. Karim Benzema scored twice after Angel Di Maria opened the scoring.
The match pits Everton manager Roberto Martinez against a team from his native country, Spain.
Cristiano Ronaldo threw out the ceremonial first pitch at Dodger Stadium -- the setting for Saturday's clash -- on Wednesday night.
The winner of this game will go up against the winner of Chelsea-AC Milan for the ICC final, while the losers will duke it out for third place. Regardless, all teams in the ICC will travel to Miami for the final placing matches in the tournament.
Should Madrid and Chelsea advance, Jose Mourinho would get the chance to coach against Los Blancos just months after leaving the club to return to London.