Blake Griffin led the Clippers with 19 points and eight rebounds.
The NBA champion Heat will play the Clippers again Sunday in Shanghai.
New addition Ray Allen had 15 points off the bench for Miami, hitting four 3-pointers.
Dwyane Wade played in his first preseason game after surgery on his left knee but shot just 2 for 9, finishing with five points.
- Los Angeles Clippers
- Miami Heat