The team's top receiver was injured in the fourth quarter of a 23-0 loss to the Seattle Seahawks on Sunday.
Cruz left 2 yards short of his third straight 1,000-yard season. He caught two passes for 25 yards before getting hurt.
The Giants (5-9) have two games left. They are stuck with their first losing year since 2004.
Huber was down on the field for several minutes. His mouth was bloody as he walked to the Bengals' locker room with what the team called a ''dental injury.''
Bengals linebacker James Harrison, making his first appearance in Pittsburgh since signing with the Bengals in the offseason, left in the first quarter because of a concussion.
The Dallas Cowboys and Green Bay both lost players in the Packers' 37-36 win.
Starting defensive end Johnny Jolly came out with a shoulder injury in the first half. He didn't return.
Packers tight end Brandon Bostick also left with a foot injury.
After Dallas starting linebacker Justin Durant exited with a hamstring, backup linebacker Ernie Sims needed X-rays when he hurt his left hip on the final play of the first half.
Jacksonville backup guard Mike Brewster broke his left ankle in the Jaguars' 27-20 loss to Buffalo.
The Cleveland Browns lost star cornerback Joe Haden in the second half with a hip pointer. His absence allowed Chicago quarterback Jay Cutler to pick on rookie cornerback Leon McFadden in the Bears' 38-31 win.
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- American Football
- New York Giants
- Victor Cruz
- Seattle Seahawks
- Kevin Huber