Samuel, a four-time Pro Bowl selection, was limited in practice Friday for the first time this week. A similar thigh injury sidelined him at New Orleans three weeks ago.
Atlanta (1-2) hosts New England (3-0) on Sunday.
Jones leads the NFL with 373 yards receiving. His 27 catches are tied with New England's Julian Edelman for most in the league.
The Falcons said that running back Steven Jackson (hamstring) won't play.
The Patriots list two-time Pro Bowl tight end Rob Gronkowski (back, forearm) as questionable. Gronkowski has yet to play this season.
AP NFL website: http://pro32.ap.org/poll
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- American Football
- Atlanta Falcons
- Asante Samuel
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- Julio Jones