HOUSTON (AP) -- Matt Dominguez hit a grand slam and drove in a career-high five runs to back another solid performance by Jordan Lyles, and the Houston Astros rolled to a 10-1 win over the Milwaukee Brewers on Tuesday night.
Carlos Pena had a three-run homer and Chris Carter had two hits and drove in a run as the Astros won for the fifth time in six games.
The 22-year-old Lyles (4-1) yielded seven hits and one run over seven innings. It was his seventh straight start with two or less earned runs.
The Astros were up by one in the fifth when Pena launched his home run to chase Milwaukee starter Alfredo Figaro and extend the lead to 5-1. Dominguez's first career grand slam was off Tom Gorzelanny and came in Houston's five-run seventh.
Figaro (1-1) was unable to build on his last start when he pitched seven shutout innings in a win over Miami. He allowed five hits and four runs in a season-low 4 1-3 innings.
Dominguez entered the game in a 0-for-7 slump before using his two hits to drive in five runs and give him 40 RBIs this season to pass Carter for the team lead. He has 10 homers in his last 35 games after not homering in his first 33 games this season.
J. D. Martinez reached on third baseman Yuniesky Betancourt's second error of the game with one out in the seventh. Carter hit an RBI double off Burke Badenhop and he was replaced by Gorzelanny.
Gorzelanny struggled with control from the outset, plunking Pena before walking Justin Maxwell on four pitches to load the bases for Dominguez.
Dominguez gave Houston its first grand slam of the season when he hit a drive into the Crawford Boxes in left field.
Houston's big offensive night got started when Martinez singled to start the second. Dominguez later hit a sacrifice fly.
Juan Francisco started the Milwaukee third with a triple which bounced on Tal's Hill in center field. The Brewers tied it with a single by Scooter Gennett.
Jean Segura and Carlos Gomez hit back-to-back singles to load the bases with one out, but Lyles retired the next two batters to limit the damage.
Maxwell, in his first game back after breaking his left hand on April 23, walked and reached third on a single by Dominguez in the fourth. The Astros took a 2-1 lead when he scored on a bunt by Marwin Gonzalez.
Gomez made an acrobatic catch on the hill in center field to rob Jason Castro of a hit in the seventh inning.
NOTES: Castro celebrated his 26th birthday on Tuesday. ... The series continues on Wednesday when Milwaukee's Kyle Lohse opposes Erik Bedard. ... The Astros traded minor league OF Fernando Martinez to the New York Yankees for minor league RHP Charles Basford.