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SAN DIEGO -- Struggling Arizona right-hander Bronson Arroyo found the perfect remedy for a slow start to the 2014 season -- the inoffensive San Diego Padres.

Arroyo blanked San Diego on three hits over seven innings Friday night to lead the Diamondbacks to a 2-0 victory in the opener of a 10-game homestand for the Padres.

The shutout was the fifth of the season -- and the third in the last six games -- for a Padres team that ranks last in the National League in hitting (.214) and last in the Major Leagues in runs scored (2.6 runs per game).

Arroyo's best outing of the season continued his dominance of the Padres. He is 4-0 against the Padres in his last five starts against San Diego with a 1.54 earned run average). He improved to 2-2 on the season with a 6.03 ERA.

The Padres had only five baserunners against Arroyo. San Diego managed to advance two runners to third, both reaching with two out. Arroyo got out of both jams by ending the inning on a ground out.

Right-handers Brad Ziegler and Addison Reed each worked a perfect inning to preserve the shutout. Reed picked up his seventh save.

Arizona took advantage of some uncustomary wildness by Cashner to score twice in the third.

Diamondbacks lead-off hitter Gerardo Parra drew a one-out walk from Cashner. The right fielder advanced to third on first baseman Paul Goldschmidt's two-out, ground single through the right side.

Cashner, who had issued 12 walks in the first 42 2/3 innings this season, then walked catcher Miguel Montero on a full-count pitch to load the bases. Second baseman Aaron Hill dropped a single in front of Padres left fielder Seth Smith to score Parra and Goldschmidt.

Cashner (2-4, 2.72 ERA) allowed two runs on four hits and three walks over six innings to suffer his third straight loss.

Arroyo entered the game with a 7.77 ERA and a .346 opponents' batting average after his first five starts. He got off to another slow start Friday night when he bobbled shortstop Everth Cabrera's lead-off grounder to the right side for an error.

But Cabrera was eliminated on a double play as Arroyo faced the minimum number of Padres through 4 1/3 innings. First baseman Yonder Alonso then ended his own 0-for-27 drought with a line drive single to right to end the no-hitter bid.

NOTES: Padres RHP Casey Kelly and LF Carlos Quentin will both start their rehab assignments with Single-A Lake Elsinore Saturday night. Kelly, who had Tommy John surgery on April 1, 2013, is scheduled to throw four innings or 60 pitches. Quentin, who has been on the disabled list since the end of spring training with a bone bruise in his left knee, is scheduled to make at least three or four starts for the Storm. The Diamondbacks promoted OF Alfredo Marte from Triple-A Reno and optioned OF Tony Campana to the same team ... The Padres officially announced the signing of 27-year-old Cuban RHP Odrisamer Despaigne ... Padres 3B Chase Headley (calf strain) might be ready to start playing on a rehab assignment early next week ... 1B Paul Goldschmidt set a Diamondbacks franchise record with 40 hits in March-April. The old club record was 37 by 2B Orlando Hudson in 2007.
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