DePaul (6-3) used an early 14-0 run to jump out to a 21-8 lead. Moses Morgan made two 3-pointers and made a nice pass to Cleveland Melvin for an alley-oop dunk during the span for the Blue Demons.
Brandon Young scored 13 points and Melvin finished with 11 points and three blocks in a game where DePaul led by as many as 41. The Panthers beat the Blue Demons last season.
DePaul held Milwaukee's leading scorer Jordan Aaron to six points on 2-for-11 shooting. Paris Gulley led Milwaukee (3-7) with 14 points.
The Blue Demons held Milwaukee to 25.8 percent shooting and forced 17 turnovers.
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