Notre Dame's series with Michigan will end after the 2014 season.
The Fighting Irish have opted out of their contract, according to reports Tuesday, for scheduled games in 2015 through 2017.
The storied programs have met on the football field since 1978.
Notre Dame's recent announcement that it would join the Atlantic Coast Conference and play five football games yearly against ACC opponents preceded the termination of the rivalry.
The Detroit Free Press reported that a three-year notice is required to pull out of the agreement and that Michigan received a letter from Notre Dame before Saturday night's game in South Bend, Ind., stating its intentions.
The two teams were scheduled to break from their scheduled series in 2018-19, but Michigan had hoped it would resume in 2020.
--The Sun Belt Conference has suspended Western Kentucky safety Jonathan Dowling for one game as the result of a helmet-to-helmet hit during Saturday's game against Southern Mississippi.
Dowling, who is tied for the FBS lead in interceptions with four, was ejected from the game after the collision and likely will miss the Hilltoppers' next conference game against Arkansas State.
Western Kentucky officials are appealing the ruling.
--- LSU and TCU confirmed that the two schools will open the 2013 season in the Cowboys Classic on Aug. 31 at Cowboys Stadium in Arlington, Texas.
--- USC defensive back Brian Baucham remains hospitalized because of an unspecified breathing problem that occurred in Saturday's game against Cal, the Los Angeles Times reported.
Baucham was on a ventilator in intensive care on Saturday and Sunday, according to the report, but he was no longer on a ventilator Monday and his condition had improved.