LOS ANGELES -- The wakeup call arrived a bit late for the Los Angeles Clippers on Monday, and when it finally came, a groggy, road-weary club still needed a cup of coffee or two to finally rouse itself against the San Antonio Spurs.
When the Clippers finally came to life, they wiped out a big deficit and emerged with a 115-92 victory at sold-out Staples Center.
Clippers forward Blake Griffin scored a game-high 27 points to go along with nine rebounds. He keyed a second-quarter run that sent the Spurs reeling and changed the complexion of the evening as the Clippers (17-9) climbed out of a 10-point hole to take a nine-point lead.
The win was the biggest ever for the Clippers over the Spurs (19-5).
Point guard Chris Paul added 23 points, eight rebounds and seven assists for Los Angeles, which improved to 9-2 at home.
Forward Tim Duncan had 17 points and 11 rebounds for the Spurs, who could not recover from the Clippers' 19-0, second-quarter surge -- not to mention the loss of point guard Tony Parker late in the third quarter with a right shin bruise.
San Antonio fell to 10-3 on the road.
The Clippers, who were playing at home for the first time after a seven-game road trip, sank 11 3-pointers, four coming from guard Jared Dudley, who had 14 points. Guard Jamal Crawford added three 3-pointers and finished with 17 points.
Shooting guard Manu Ginobili had 16 points off the bench for the Spurs. He was forced into the point guard position in relief Parker, who had eight points and six assists in 26 minutes before limping off the court with 5:09 remaining in the third quarter.
Forward Kawhi Leonard had 12 points for the Spurs, who drew within 59-58 early in the third quarter. San Antonio was in striking distance in the fourth quarter until the Clippers took over with a 14-4 run to take a 106-86 lead with 2:15 left in the game.
The Spurs led 31-21 early in the second quarter before the Clippers' 19-0 run.
Duncan finally snapped the streak by sinking two free throws with 5:34 left in the half. San Antonio guard Marco Belinelli two added 3-pointers, slicing the Clippers' lead to 42-39.
Griffin and Paul finished the half with 19 and 14 points, respectively, as Los Angeles took a 55-49 lead into the break.
Duncan had 13 first-half points.
NOTES: The Clippers were back home for the first time after a seven-game road odyssey covering 13 days. The trip didn't go nearly as well as planned, but they finished 4-3 while returning to potentially good news. Injured G J.J. Redick is expected to get the cast removed from his broken hand within the next two weeks and is now hopeful of a Jan. 15 return. That would be two weeks sooner than expected after Redick broke the hand Nov. 29. ... C Tiago Splitter went through a full-speed workout during the Spurs' morning shoot-around and was cleared to play against the Clippers. Splitter was sidelined the previous four games due to left calf tightness.