Srna, Chygrynskiy, Rakytskyy, Rat
Teixeira, Mkhitaryan, Douglas Costa
Piszczek, Subotic, Hummels, Schmelzer
Blaszczykowski, Gotze, Reus
Borussia Dortmund will be boosted by the return of defenders Marcel Schmelzer and Neven Subotic. The former had missed Germany's friendly with a foot injury, while the latter had been struggling with a hamstring problem.
Ilkay Gundogan is also out after picking up a knock, with Nuri Sahin set to feature again, but Kevin Grosskreutz will miss this game as he battles pneumonia.
Shakhtar, meanwhile, has an empty spot on the right wing following the January departure of Willian. Alex Teixeira is expected to fill in for his compatriot, though Taison could make his debut.
Olexandr Kucher is suspended, leaving either Dmytro Chygrynskiy or Sergey Krivtsov to partner Yaroslav Rakytskyy at the back. Either Tomas Huschmann or Taras Stepanenko will cover the defense alongside Fernandinho.