The Knights (18-6, 7-3 Conference USA) needed a 3-pointer from Marcus Jordan with 14.3 seconds to play to stop a Thundering Herd rally that had cut a 14-point deficit to just two in the final minute.
Marshall (14-10, 5-5) was led by Damier Pitts with 18 points and seven assists.
Clanton was the driving force for Central Florida in both halves. His follow shot completed a 13-2 run early in the second half that allowed the Knights to pull out to a 44-34 lead with 11:54 left.
Marshall was down 58-44 when Pitts started and finished a 16-4 run with 3-pointers that got the Thundering Herd within 62-60 with 49.7 seconds left in the game.
- Central Florida