Bush, who is bothered by a banged-up left knee, was limited in practice Friday. So was Fairley, who has been bothered by a shoulder problem and was inactive against Arizona last weekend.
The Lions acquired Bush in the offseason as a running threat to complement quarterback Matthew Stafford and receiver Calvin Johnson. He ran for 90 yards and caught a 77-yard touchdown pass in a season-opening win over Minnesota.
In a loss to Arizona, Bush was held to 25 yards on nine carries.
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