Sanders and Mayo have both missed practice the last couple days. Coach Larry Drew said Sanders had a cold, while Mayo had flu-like symptoms.
Sanders is the team's second leading rebounder (6.7 per game) while Mayo is averaging 12.6 points off the bench.
Milwaukee planned to go with a big starting frontcourt of Ekpe Udoh, Ersan Ilyasova and John Henson, who are each at least 6-foot-10, to counter the Pistons' physical front line of Josh Smith, Greg Monroe and Andre Drummond.
The Bucks have the worst record in the NBA at 7-33. They're trying to snap a nine-game losing streak.
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