SAN DIEGO -- Mark DeRosa's tiebreaking home run in the top of the 11th inning helped the Toronto Blue Jays earn a 7-4 victory over the San Diego Padres on Sunday evening.
DeRosa's blast traveled 428 feet into the second deck in left field, keeping the second extra-inning game in the three-game series much shorter than Friday's 17-inning affair.
Brad Boxberger, called up earlier Sunday from Triple-A Tucson, took the loss. Before recording an out, Boxberger (0-1) gave up five straight hits, including an RBI double from Jose Bautista and DeRosa's fourth home run.
Casey Janssen (1-0) pitched a scoreless 10th, and Aaron Loup recorded his second save in three opportunities. The Toronto bullpen allowed just two hits in nine shutout innings.
The Blue Jays, who salvaged a game in their first-ever series in San Diego, are 2-3 on a seven-game road trip.
The game was deadlocked from the fifth inning on, thanks to solid work from the Blue Jays bullpen and the Padres defense.
Padres starter Edinson Volquez allowed four runs and six hits in five innings as he struggled with the location of pitches. He walked three, threw a wild pitch and struck out seven.
His best moment came at the plate. The lifetime .090 hitter connected on the first career home run of his major league career in the second inning to give the Padres a 4-1 lead.
Blue Jays starter Ramon Ortiz left the game with no outs in the third inning after apparently injuring his right elbow. A day after being outrighted to the minor leagues, the 40-year-old veteran was promoted Saturday from Triple-A Buffalo to start Sunday in place of Brandon Morrow (forearm).
Ortiz, who allowed four runs in two-plus innings, appeared to get hurt while delivering a pitch. Ortiz's left knee buckled when it planted, but he immediately grabbed his right elbow and threw his glove down in frustration.
Ortiz's injury was not disclosed during the game. The right-hander left the field in tears and was replaced by Brad Lincoln, who pitched two scoreless innings and left with the game tied.
The Blue Jays made it 4-4 in the fifth on Adam Lind's two-run double off the center field wall.
The Padres scored four runs off Ortiz in the second, an inning highlighted by Volquez's three-run homer. Ortiz walked Will Venable to face the Padres pitcher, who hit an elevated offering into the seats beyond left field.
That gave the Padres a 4-1. Earlier in the second inning, Jedd Gyorko hit an RBI double to left-center.
The Blue Jays cut the lead to 4-2 in the third inning on Edwin Encarnacion's 16th home run of the season.
Toronto jumped on top in the second when Colby Rasmus' double off the wall in left-center scored Lind.
NOTES: The Padres recalled RHP Brad Boxgerber from Triple-A Tucson and optioned LHP Robbie Erlin. Erlin was promoted for a spot start Saturday, which he won by allowing two runs in 6 2/3 innings. Boxberger is a relief pitcher. ... Blue Jays LF Melky Cabrera balked at the idea of a rough return to San Francisco when the Blue Jays play there Tuesday. Cabrera was suspended 50 games last season, while with the Giants, for violating the league's policy on performance-enhancing drugs. He was not added to the team's postseason roster despite being eligible. ... RHP Josh Johnson (triceps) will come off the 15-day disabled list just prior to Tuesday's game at San Francisco and is scheduled to start that night. ... Padres RHP Joe Wieland, on the disabled list since having Tommy John surgery in July 2012, threw live batting practice for the first time since his operation.