TORONTO -- Brett Lawrie drove in the winning run with a one-out single in the 10th inning to give the Toronto Blue Jays a 4-3 victory over the Boston Red Sox on Wednesday.
The Blue Jays' victory before a crowd of 31,695 at Rogers Centre snapped a three-game losing streak. The teams will play the rubber match in the three-game series on Thursday.
Mike Napoli tied the game 3-3 with a two-run homer with two out in the ninth.
Rajai Davis opened the bottom of the 10th with a double to left center against right-hander Brandon Workman (3-2), who entered the game with one out in the seventh.
Davis took third on a slow ground out to third by Jose Bautista. Edwin Encarnacion was intentionally walked to set up Lawrie's hit that was deflected in the infield.
Napoli's homer deprived Toronto right-hander Esmil Rogers of his first win since June 18 after he held the Red Sox to one run on a home run by David Ortiz over six innings. He allowed five hits and one walk and struck out six.
Right-hander Neil Wagner took over in the seventh inning and retired six batters in a row. That set up left-hander Brett Cecil to pitch the ninth, and he allowed a walk to Jonny Gomes with one out and Napoli's 15th homer of the season with two out to tie the game at 3.
The Red Sox then loaded the bases when Jarrod Saltalamacchia doubled, Will Middlebrooks was hit by a pitch and Jacoby Ellsbury hit an infield single. But right-hander Brad Lincoln (1-1) came in to retire Shane Victorino on a fly to left.
Lincoln stayed in to get the win.
Boston left-hander Jon Lester allowed six hits and three runs (two earned) in 6 1/3 innings.
Ortiz lined a 3-2 slider to right center for his 23rd homer of the season in the sixth to cut Toronto's lead to 2-1.
The Blue Jays regained their two-run lead in the bottom of the sixth when Encarnacion and J.P. Arencibia hit doubles.
Davis went all the way around the bases to score on the Blue Jays' first hit of the game, his infield single that was followed by two throwing errors on the same play.
Davis hit a one-hopper off Lester's leg. The pitcher retrieved the ball and threw errantly to first. Davis kept churning to third and Victorino threw wildly to third and Davis to romp home.
The Blue Jays led 2-0 after Encarnacion and Mark DeRosa hit doubles in the fourth.
NOTES: The Blue Jays traded INF-OF Emilio Bonifacio to the Kansas City Royals for a player to be named and cash considerations on Wednesday. ... CF Colby Rasmus (left oblique strain) was put on the 15-day disabled list. ... INF Munenori Kawasaki and OF Kevin Pillar were called up from Triple-A Buffalo. .... Boston RHP Clay Buchholz (shoulder) was encouraged by the results of Wednesday's bullpen session of about 50 pitches and is scheduled for another session on Saturday. ....LHP Mark Buehrle (8-7, 4.43 ERA) will pitch the series finale on Thursday for Toronto against Boston RHP Jake Peavy (9-4, 4.50 ERA).