Coach Doug Marrone was able to provide a more definitive timetable on Manuel's recovery Wednesday after consulting with team doctors. Manuel began working out on his own Tuesday for the first time since being hurt in a loss to Cleveland on Oct. 3.
Manuel has an opportunity to return before the Bills have their bye week off on Nov. 24.
Thad Lewis, who was promoted off the practice squad last week, is set to make his second consecutive start Sunday, when Buffalo (2-4) plays at Miami (3-2). Lewis practiced fully on Wednesday after hurting his right foot in a 27-24 overtime loss to Cincinnati last weekend.
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