GLENDALE, Ariz. -- Center Ryan O'Reilly scored a power play goal with 41.1 seconds remaining in overtime Thursday to extend the best start in Colorado Avalanche history.
The Avalanche emerged with a 4-3 victory over the Phoenix Coyotes at Jobing.com Arena.
Colorado (16-5-0) has a franchise record for victories and points through its first 21 games under first-year coach Patrick Roy.
Avalanche forward Cody McLeod tied the game at 3 at 16:46 of the third period on a backhand shot in front. Defenseman Andre Benoit sent a pass from the point to McLeod, who broke a streak of three consecutive Phoenix goals.
Center Antoine Vermette gave the Coyotes a 3-2 lead at 14:06 of the third period when he scored from point-blank range on a pass from right winger Shane Doan, who scored a point in a seventh consecutive game.
The Coyotes (14-4-4) are 9-0-2 at home, only one of two teams that has not lost in regulation at home.
Colorado, 14-0 when its scores first this season, earned its second win in a row after a three-game losing streak.
Avalanche goaltender Semyon Varmalov made 41 saves while improving to 11-5 this season.
Goalie Mike Smith had 26 saves for the Coyotes, suffering his second loss in 11 career meetings against Colorado.
Colorado center John Mitchell scored seven seconds into the Avalanche's first power play of the night for a 1-0 lead less than a minute into the second period.
Avalanche right winger P.A. Parenteau won a faceoff in the right circle immediately after the penalty was assessed, and the puck moved toward the Coyotes' net. Nathan MacKinnon had a short shot blocked in the slot before Mitchell found the top of the net for his fourth goal of the season.
Benoit, who was taken to the dressing room after being struck in the face by a shot midway through second period, scored his first goal of the season at 15:50 of the second period for a 2-0 lead.
Benoit's shot from near the blue line in the middle of the zone found the top left corner of the net. Smith appeared to be screened by Colorado left winger Gabriel Landskog on the play.
Phoenix defenseman Martin Stone cut the deficit to 2-1 when his shot from just inside the red line skipped past Varlamov at 17:10 of the period. Stone has seven goals, tied with Ottawa's Erik Karlsson for the most goals by a defenseman.
Coyotes center Martin Hanzal tied the game at 2 with his seventh goal of the season at 10:40 of the third period, when he poked in a rebound of a shot by left winger Tim Kennedy. Hanzal's goal came with three seconds left in a Phoenix power play.
NOTES: Coyotes G Mike Smith made at least 40 saves in a game twice this season, and has an NHL-high 14 such games since the start of the 2011-12 season, when he became the starter in Phoenix. ... Colorado C Matt Duchene (oblique) missed his second straight game and is expected to be out at least a week, the Avalanche said. Duchene leads the team with 12 goals and 20 points. ... Coyotes D Oliver Ekman-Larsson played his 200th NHL game. He has 16 points, fifth among defensemen through Wednesday, and a plus-12 rating, tied for first in the NHL a quarter of the way through the season. ... The Coyotes had not played since Thursday, when they beat the Tampa Bay Lightning 6-3. The only longer stretch they will have between games this season will be the break for the Olympic Games in February.