The Astros can secure their third straight winning series in Anaheim with a fourth consecutive victory overall Tuesday night.
Houston (17-28) has been outscored 64-32 while losing nine of 11 at home versus Los Angeles, but owns a 40-23 run advantage while taking seven of eight at Anaheim. Dallas Keuchel came within an out of his second straight shutout and Jason Castro and Matt Dominguez each had two hits with one RBI in a 5-2 victory in Monday's opener of this three-game set.
In the midst of their longest winning streak since a four-game run Sept. 9-13, the Astros are averaging 5.7 runs and batting .302 while winning five of six.
"It's fun right now," Keuchel said. "A lot of people are seeing what we're capable of doing.''
A southern California native, Dominguez is batting .366 with six RBIs in his last 10 games and is 8 for 17 in the last four on the road.
With two hits Monday, teammate Jose Altuve is batting .400 (20 for 50) during an 11-game hitting streak.
The Astros will hand the ball to Scott Feldman (2-1, 2.63 ERA), who allowed a run and three hits in seven innings of a 7-4 home win over the Angels on April 6.
''I don't think he did anything that we didn't expect,'' Los Angeles manager Mike Scioscia said after that contest.
The right-hander posted an 8.68 ERA while losing two straight starts at Anaheim with Texas before allowing two runs in six innings while not factoring in a 4-3 defeat there for the Chicago Cubs on June 4. He's yielded two runs and seven hits over 13 innings while not factoring in the decision in his two road starts this year.
Feldman has a 4.91 ERA without a decision in two starts since missing three weeks with biceps tendinitis. He gave up four runs and 10 hits in five innings of a 5-4 victory over the Rangers on Wednesday.
"It's kind of frustrating a little bit, but I kept the team in the game as well as I could," Feldman told the Astros' official website. "We ended up with the win, so that's the main thing."
Batting .450 (9 for 20) with a homer versus Feldman, Howie Kendrick delivered a two-run triple in the ninth as the Angels (24-20) fell for the third time in 11 games.
Teammate Mike Trout had a hit in the opener but is batting .158 in his last 16 games. He hasn't had a multihit game since April 28, and is 1 for 6 versus Feldman.
Scheduled Angels starter Tyler Skaggs (3-1, 4.53) has a 1.57 ERA in winning his three road starts this season, but is 0-1 with a 6.91 ERA in five home outings. He allowed five runs and eight hits in six innings of a 6-5 home victory over Tampa Bay on Thursday.
In the left-hander's only previous appearance against the Astros, Skaggs gave up a run and four hits in eight innings of a 5-1 win April 5.
Altuve and Dominguez went a combined 1 for 5 versus Skaggs in that contest.