Simon (12-3), who was the first NL pitcher to reach 12 wins is tied with St. Louis' Adam Wainwright for the league lead.
Cueto started Sunday for Cincinnati and will most likely not be available to pitch on Tuesday.
This is Simon's first All-Star game.
The previous time the Reds had as many as five All-Stars was in 1991 - pitchers Tom Browning and Rob Dibble, shortstop Barry Larkin, right fielder Paul O'Neill and third baseman Chris Sabo.
- Sports & Recreation
- Alfredo Simon
- Cincinnati Reds
- Johnny Cueto
- Adam Wainwright
- Aroldis Chapman
- Devin Mesoraco