The Bulldogs hit 45.7 percent from the field overall, 52.4 percent from the line and 70.4 percent from 3-point range.
Alabama A&M went 14-3 to start the contest, led 30-25 at halftime and had no trouble pacing Prairie View in the second half for the win, handing the Panthers their fourth-straight conference loss.
Montrael Scott led the Panthers (8-19, 6-9) with 15 points. Louis Munks added 14 points and six rebounds.
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