Tia Magee’s three-point play with 48.7 seconds left gave the Hoyas a 58-49 lead and finally some breathing room against a pesky George Washington team.
In what was once an annual matchup, Georgetown (9-2) won the first game between the crosstown rivals since 2004.
George Washington (5-4), which had its four-game winning streak snapped, still leads the all-time series 17-15.
Magee finished with nine points and matched career-highs with 13 rebounds and five steals to help the Hoyas avoid their first regular-season nonconference home loss since Dec. 17, 2006.
Danni Jackson had 10 points, eight steals and four rebounds for the Colonials while Tara Booker scored 10 points.