Texas (3-1) rolled to a 43-25 halftime lead. Ashleigh Fontenette had 11 points and six assists and Anne Marie Hartung added 10 points and had a game-high eight rebounds for the Longhorns, who held a 40-24 edge on the boards.
Texas led 11-9 when it went on a 13-0 run, and the Longhorns led by as many as 26 points in the first half.
Ariana Moorer led Virginia (4-1) with 17 points and China Crosby added 12 points. The Cavaliers shot just 31 percent from the field.