Colton Iverson had 10 points and Daniel Bejarano shared rebounding honors with seven. Colorado State was 7 for 11 from 3-point range and extended its seven-point halftime lead to as many as the final margin of 28.
Travis Wallace led the Ospreys (3-7) with 12 points. Parker Smith added 10 points.
The Rams owned a 41-23 rebounding edge and held North Florida to 43 percent shooting—36 percent in the second half.