Adenrele had 13 points and 10 rebounds. Les, who came off the bench, was 4 of 6 from 3-point range.
Three other Aggies scored in double figures. Josh Ritchart had 14 points, and Ryan Sypkens and Paolo Mancasola had 10 apiece.
UC Davis (2-6) never trailed in the game and led 40-32 at halftime.
The Aggies had just four turnovers and shot 50 percent from the field for the game, while Eastern Washington shot 33 percent.
Parker Kelly had 17 points for Eastern Washington (2-8). Justin Crosgile had 15 points, and Thomas Reuter had 10. Venky Jois led with 12 rebounds.
With the win, UC Davis broke its four-game losing streak.