Josh Huestis added 14 points and nine rebounds for the Cardinal (7-3), who have won four of their last five games. Chasson Randle scored 12 points.
J.T. Adenrele scored a career-high 23 points to pace the Aggies (1-6), who lost their fourth straight. Corey Hawkins added 10 points.
Powell made his first eight shots of the second half after being limited to two minutes in the first half due to foul trouble.
Ryan Sypkens, who entered the game as one of the nation’s top 3-point shooters, was limited to a pair of 3-pointers, his fewest since connecting on one in the Aggies’ season-opening loss at Oklahoma.