South Dakota State (24-7, 15-3 Summit League) endured a difficult first half in which it trailed by as many as 11 and entered halftime scoring five unanswered points to lead 37-35. The Jackrabbits emerged a different team in the second half, outscoring IUPUI (14-17, 7-11) 38-29 en route to a comfortable margin of victory.
Nate Wolters contributed 15 points for the Jackrabbits, who shot 50 percent from the floor, including 47.1 percent from 3-point distance.
Ian Chiles led with 17 points and Alex Young chipped in with 16 for the Jaguars.
South Dakota State finished the season 14-0 at home, its third undefeated season at Frost Arena.