The Bulls are a league-worst 3-34 on the road but are 22-12 at the United Center. They have won three in a row here since a 103-97 loss to the Los Angeles Clippers on March 8.
Chicago, which has lost four of six overall, dropped its seventh straight road game on Sunday with a 105-82 blowout defeat at Detroit.
Chicago has lost eight of 10 meetings with the Heat over the last three seasons, including a 102-101 overtime setback at Miami on January 18 and a 100-90 road defeat on February 22. This is their final matchup of the season.
The Heat lost for the 10th time in 12 games on Tuesday, 108-91 at Minnesota.
Rookie Caron Butler scored 21 points to lead Miami, which shot just 42 percent.