The Magic have won the first three matchups with the Heat this season, including a 100-86 triumph here on October 30.
Orlando has gone 3-1 against Miami twice, in the 1994-95 and 1995-96 campaigns.
The Magic capped a four-game homestand on Friday its third straight win, a 109-85 triumph over Cleveland.
Tracy McGrady went 12-of-21 from the field and 12-of-13 from the arc en route to a 39-point performance in just 30 minutes.
Darrell Armstrong added 14 points but was the only other player in double figures for Orlando, which is in seventh place in the Eastern Conference, 2 1/2 games in front of eighth-place Milwaukee.
Miami had lost eight of nine before defeating Toronto here on Friday, 107-98.