The Spurs, who have won four games in a row, capped a three-game road trip with a 111-99 triumph at Minnesota on Wednesday.
The Clippers, who have lost two in a row and 10 of 11, are coming off a heartbreaking 118-114 overtime setback at Houston on Wednesday.
With the game tied, 104-104, and 1.1 seconds left in regulation, Andre Miller was fouled and attempted two free throws. He sank the first but it was disallowed by referee Jim Clark for stepping over the line. Television replays indicated the ball went through the net before Miller went over the line. Miller missed his second attempt, and the game went into overtime.
The Spurs have won two of the first three meetings between the teams this season, including a 97-84 victory here on December 12.