The Grizzlies, who won four in a row - one shy of their franchise-record streak - from December 8-13, followed up a 26-point win at Cleveland on Saturday with a 119-106 win at Toronto on Sunday.
The Grizzlies are aiming for their first three-game road winning streak since February 16-20, 2001.
The Knicks, who have won back-to-back games, are aiming for their first three-game winning streak since January 18-22.
On Sunday, New York edged Washington, 97-96, in what was likely Michael Jordan’s final game at Madison Square Garden.
The Knicks defeated the Grizzlies in Memphis on January 31, 108-102. The Knicks are 10-3 all time against the Grizzlies, including 5-1 here.