The Heat have won their last four meetings with the Bulls, including a 102-101 double-overtime victory on January 18. They have won eight of their last 10 meetings with Chicago, which has a 34-19 advantage in the all-time series.
The Bulls have won three of their last five visits to American Airlines Arena and are 19-8 all time in Miami.
Miami completed a 1-3 road trip with an 84-79 loss to the New Jersey Nets on Tuesday.
Miami has lost three in a row and is trying to avoid its first four-game losing streak since a six-game slide from January 3-12.
Chicago has dropped 10 of its last 12 games, including a 110-96 loss at Orlando on Friday.