The Heat, who are opening a four-game road trip, capped a 1-3 four-game homestand with a 78-69 setback to New Orleans on Tuesday.
The Heat shot just 36 percent in the defeat.
Jones, Miami’s leading scorer, will miss the game and Saturday’s contest at Dallas because of a strained left groin aggravated in the loss to the Hornets, though he may rejoin the team for games Monday and Tuesday at Detroit and New Jersey. The Heat went 1-6, including 0-5 on the road, last month when Jones was hampered by a sprained right ankle.
Houston had lost three in a row before routing Utah at the Delta Center on Wednesday in the back end of a home-and-home series, 106-76.
The Rockets defeated the Heat in Miami on December 16, 105-100 in overtime. Francis sent the game into an extra session with a 3-pointer at the buzzer.
The Heat have won the last two matchups in Houston.