| Pitching | G | GS | W | L | SV | BS | HLD | CG | SHO | IP | H | R | ER | HR | BB | K | ERA | WHIP | BAA |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Totals | 165 | 86 | 83 | 24 | 73 | 146 | 4.36 | 1.39 | .256 | ||||||||||
| League Rank | 3 | 7 | T8 | T17 | T16 | 7 | 21 | 20 | T14 | ||||||||||
| Mark Melancon | 9 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 9.0 | 9 | 0 | 0 | 0 | 1 | 9 | 0.00 | 1.11 | .265 |
| Justin Wilson | 6 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 11.2 | 2 | 2 | 2 | 0 | 3 | 13 | 1.54 | 0.43 | .057 |
| Francisco Liriano | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5.1 | 6 | 1 | 1 | 0 | 2 | 9 | 1.69 | 1.50 | .286 |
| Jeff Locke | 4 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 25.0 | 16 | 5 | 5 | 0 | 8 | 16 | 1.80 | 0.96 | .193 |
| Jared Hughes | 7 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 8.2 | 7 | 2 | 2 | 0 | 6 | 6 | 2.08 | 1.50 | .233 |
| Bryan Morris | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4.1 | 2 | 1 | 1 | 1 | 0 | 4 | 2.08 | 0.46 | .167 |
| Jason Grilli | 10 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 0 | 8.1 | 7 | 2 | 2 | 0 | 1 | 9 | 2.16 | 0.96 | .226 |
| A.J. Burnett | 3 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 16.1 | 14 | 5 | 5 | 0 | 10 | 22 | 2.76 | 1.47 | .233 |
| Jeanmar Gomez | 5 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 14 | 8 | 7 | 4 | 7 | 9 | 3.50 | 1.17 | .215 |
| Vin Mazzaro | 7 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 8.0 | 11 | 5 | 5 | 1 | 1 | 5 | 5.63 | 1.50 | .344 |
| Wandy Rodriguez | 4 | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 17.2 | 23 | 13 | 12 | 6 | 6 | 9 | 6.11 | 1.64 | .303 |
| Chris Leroux | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.0 | 4 | 3 | 3 | 1 | 6 | 3 | 6.75 | 2.50 | .267 |
| Tony Watson | 8 | 0 | 0 | 0 | 1 | 0 | 3 | 0 | 0 | 8.2 | 9 | 7 | 7 | 2 | 4 | 10 | 7.27 | 1.50 | .265 |
| James McDonald | 3 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 15.0 | 17 | 14 | 14 | 1 | 12 | 12 | 8.40 | 1.93 | .288 |
| Jonathan Sanchez | 4 | 3 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 10.2 | 21 | 16 | 16 | 7 | 5 | 10 | 13.50 | 2.44 | .404 |
| Jose Contreras | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.2 | 3 | 2 | 2 | 1 | 1 | 0 | 27.00 | 6.00 | .600 |