| Pitching | G | GS | W | L | SV | BS | HLD | CG | SHO | IP | H | R | ER | HR | BB | K | ERA | WHIP | BAA |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Totals | 228 | 102 | 93 | 27 | 98 | 240 | 3.12 | 1.21 | .232 | ||||||||||
| League Rank | 6 | 5 | 5 | T9 | 18 | 21 | 3 | T7 | T3 | ||||||||||
| Mark Melancon | 18 | 0 | 0 | 0 | 1 | 1 | 12 | 0 | 0 | 18.0 | 15 | 1 | 1 | 0 | 0 | 17 | 0.50 | 0.83 | .221 |
| Francisco Liriano | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12.2 | 8 | 1 | 1 | 0 | 4 | 16 | 0.71 | 0.95 | .170 |
| Jason Grilli | 17 | 0 | 0 | 1 | 13 | 0 | 0 | 0 | 0 | 15.0 | 7 | 2 | 2 | 0 | 3 | 25 | 1.20 | 0.67 | .137 |
| Justin Wilson | 8 | 0 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 13.2 | 7 | 2 | 2 | 0 | 7 | 9 | 1.32 | 1.02 | .159 |
| A.J. Burnett | 7 | 7 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 44.1 | 33 | 12 | 11 | 1 | 15 | 54 | 2.23 | 1.08 | .208 |
| Bryan Morris | 5 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 10.0 | 5 | 3 | 3 | 1 | 7 | 5 | 2.70 | 1.20 | .167 |
| Jeff Locke | 5 | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 27.2 | 22 | 9 | 9 | 5 | 14 | 18 | 2.93 | 1.30 | .222 |
| Wandy Rodriguez | 8 | 8 | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 44.1 | 38 | 17 | 16 | 7 | 8 | 30 | 3.25 | 1.04 | .226 |
| Jeanmar Gomez | 5 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 18.2 | 15 | 8 | 7 | 2 | 8 | 9 | 3.38 | 1.23 | .238 |
| Vin Mazzaro | 10 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 12.2 | 15 | 5 | 5 | 1 | 2 | 10 | 3.55 | 1.34 | .313 |
| Jared Hughes | 8 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 8.1 | 9 | 4 | 4 | 1 | 8 | 6 | 4.32 | 2.04 | .300 |
| Tony Watson | 15 | 0 | 1 | 0 | 0 | 1 | 6 | 0 | 0 | 15.0 | 15 | 9 | 9 | 2 | 5 | 14 | 5.40 | 1.33 | .268 |
| Jose Contreras | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.0 | 4 | 2 | 2 | 1 | 1 | 2 | 6.00 | 1.67 | .308 |
| James McDonald | 4 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 17.2 | 22 | 20 | 15 | 1 | 15 | 17 | 7.64 | 2.09 | .301 |
| Jonathan Sanchez | 3 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 7.1 | 13 | 7 | 7 | 5 | 1 | 8 | 8.59 | 1.91 | .371 |