| Pitching | G | GS | W | L | SV | BS | HLD | CG | SHO | IP | H | R | ER | HR | BB | K | ERA | WHIP | BAA |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Totals | 213 | 98 | 89 | 27 | 96 | 220 | 3.20 | 1.23 | .233 | ||||||||||
| League Rank | 10 | 7 | 6 | T11 | T21 | T21 | 6 | 12 | 5 | ||||||||||
| Mark Melancon | 16 | 0 | 0 | 0 | 0 | 1 | 11 | 0 | 0 | 16.0 | 13 | 1 | 1 | 0 | 0 | 14 | 0.56 | 0.81 | .220 |
| Jason Grilli | 16 | 0 | 0 | 1 | 12 | 0 | 0 | 0 | 0 | 14.0 | 5 | 1 | 1 | 0 | 2 | 24 | 0.64 | 0.50 | .109 |
| Justin Wilson | 7 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 12.2 | 5 | 2 | 2 | 0 | 7 | 8 | 1.42 | 0.95 | .128 |
| Francisco Liriano | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5.2 | 6 | 1 | 1 | 0 | 3 | 7 | 1.59 | 1.59 | .261 |
| A.J. Burnett | 7 | 7 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 44.1 | 33 | 12 | 11 | 1 | 15 | 54 | 2.23 | 1.08 | .208 |
| Bryan Morris | 5 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 10.0 | 5 | 3 | 3 | 1 | 7 | 5 | 2.70 | 1.20 | .167 |
| Jeff Locke | 5 | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 27.2 | 22 | 9 | 9 | 5 | 14 | 18 | 2.93 | 1.30 | .222 |
| Wandy Rodriguez | 7 | 7 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 38.1 | 32 | 14 | 13 | 7 | 8 | 25 | 3.05 | 1.04 | .222 |
| Jeanmar Gomez | 5 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 18.2 | 15 | 8 | 7 | 2 | 8 | 9 | 3.38 | 1.23 | .238 |
| Vin Mazzaro | 10 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 12.2 | 15 | 5 | 5 | 1 | 2 | 10 | 3.55 | 1.34 | .313 |
| Jared Hughes | 8 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 8.1 | 9 | 4 | 4 | 1 | 8 | 6 | 4.32 | 2.04 | .300 |
| Tony Watson | 14 | 0 | 1 | 0 | 0 | 1 | 5 | 0 | 0 | 14.0 | 14 | 9 | 9 | 2 | 5 | 13 | 5.79 | 1.36 | .269 |
| Jose Contreras | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.0 | 4 | 2 | 2 | 1 | 1 | 2 | 6.00 | 1.67 | .308 |
| James McDonald | 4 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 17.2 | 22 | 20 | 15 | 1 | 15 | 17 | 7.64 | 2.09 | .301 |
| Jonathan Sanchez | 3 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 7.1 | 13 | 7 | 7 | 5 | 1 | 8 | 8.59 | 1.91 | .371 |