| | CF | Activated (The Boston Red Sox activated OF Rob Refsnyder from the 10-day injured list.) |
| | RF | Placed on 7-Day IL (The Boston Red Sox placed OF Tyler O'Neill on the 7-day injured list.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox recalled LHP Cam Booser from the minors.) |
| | P | Placed on 15-Day IL (The Boston Red Sox placed RHP Garrett Whitlock on the 15-day injured list.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox recalled LHP Joe Jacques from the minors.) |
| | SS | Placed on 10-Day IL (González was placed on the 10-day injured list due to a wrist injury.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox recalled RHP Cooper Criswell from the minors.) |
| | P | Placed on 15-Day IL (The Boston Red Sox placed RP Isaiah Campbell on the 15-day injured list.) |
| | 3B | Recalled From Minors Rehab (The Boston Red Sox recalled INF Bobby Dalbec from the minors.) |
| | P | Placed on 15-Day IL (The Boston Red Sox placed RHP Nick Pivetta on the 15-day injured list.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox recalled LHP Brennan Bernardino from the minors.) |
| | SS | Recalled From Minors Rehab (The Boston Red Sox recalled INF Romy González from the minors.) |
| | 3B | Sent to Minors (The Boston Red Sox optioned INF Bobby Dalbec to the minors.) |
| | SS | Recalled From Minors Rehab (The Boston Red Sox recalled INF David Hamilton from the minors.) |
| | SS | Placed on 10-Day IL (The Boston Red Sox placed INF Trevor Story on the 10-day injured list.) |
| | P | Placed on 60-Day IL (The Boston Red Sox placed RHP Liam Hendriks on the 60-day injured list.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox selected the contract of LHP Joely Rodriguez from the minors.) |
| | P | Placed on 15-Day IL (The Boston Red Sox placed RHP Bryan Mata on the 15-day injured list.) |
| | SS | Placed on 10-Day IL (The Boston Red Sox placed INF Vaughn Grissom on the 10-day injured list.) |
| | CF | Placed on 10-Day IL (The Boston Red Sox placed OF Rob Refsnyder on the 10-day injured list.) |
| | P | Placed on 60-Day IL (The Boston Red Sox placed LHP Chris Murphy on the 60-day injured list.) |
| | C | Released (The Boston Red Sox released C Stephen Scott.) |
| | P | Traded (The Tampa Bay Rays traded RHP Naoyuki Uwasawa to the Boston Red Sox.) From |
| | P | Sent to Minors (The Boston Red Sox optioned LHP Brennan Bernardino to the minors.) |
| | P | Sent to Minors (The Boston Red Sox optioned RHP Zack Kelly to the minors.) |
| | P | Sent to Minors (The Boston Red Sox optioned RHP Cooper Criswell to the minors.) |
| | P | Placed on 60-Day IL (The Boston Red Sox placed RHP Lucas Giolito on the 60-day injured list.) |
| | 1B | Released (The Boston Red Sox released INF C.J. Cron.) |
| | P | Signed (The Boston Red Sox signed RHP Chase Anderson.) |
| | SS | Sent to Minors (The Boston Red Sox optioned INF Romy González to the minors.) |
| | SS | Sent to Minors (The Boston Red Sox optioned INF David Hamilton to the minors.) |
| | SS | Sent to Minors (The Boston Red Sox sent INF Nick Sogard to the minors.) |
| | P | Sent to Minors (The Boston Red Sox optioned LHP Joe Jacques to the minors.) |
| | 3B | Sent to Minors (The Boston Red Sox sent INF Dalton Guthrie to the minors.) |
| | 2B | Sent to Minors (The Boston Red Sox sent INF Nick Yorke to the minors.) |
| | C | Sent to Minors (The Boston Red Sox optioned C Tyler Heineman to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Chase Shugart to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent LHP Cam Booser to the minors.) |
| | 2B | Sent to Minors (The Boston Red Sox sent INF Jamie Westbrook to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Justin Hagenman to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent LHP Jorge Benitez to the minors.) |
| | P | Released (The Boston Red Sox released RHP Luis De La Rosa.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Andrew Politi to the minors.) |
| | P | Sent to Minors (The Boston Red Sox optioned RHP Wikelman Gonzalez to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Luis Guerrero to the minors.) |
| | P | Sent to Minors (The Boston Red Sox optioned RHP Luis Perales to the minors.) |
| | CF | Sent to Minors (The Boston Red Sox sent OF Corey Rosier to the minors.) |
| | SS | Sent to Minors (The Boston Red Sox sent INF Joe Dunand to the minors.) |
| | 2B | Sent to Minors (The Boston Red Sox sent INF Chase Meidroth to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Frank German to the minors.) |
| | C | Sent to Minors (The Boston Red Sox sent C Stephen Scott to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Alex Hoppe to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Melvin Adón to the minors.) |
| | P | Sent to Minors (The Boston Red Sox sent LHP Helcris Olivarez to the minors.) |
| | C | Sent to Minors (The Boston Red Sox sent C Nathan Hickey to the minors.) |
| | P | Sent to Minors (The Boston Red Sox optioned LHP Brandon Walter to the minors.) |
| | P | Released (The Boston Red Sox released RHP Yusniel Padron-Artilles.) |
| | P | Released (The Boston Red Sox released RHP Andrés Núñez.) |
| | P | Signed (The Boston Red Sox signed RHP Jason Alexander to a minor league contract.) |
| | P | Signed (The Boston Red Sox signed RHP Jason Alexander to a minor league contract.) |
| | P | Signed (The Boston Red Sox signed RHP Liam Hendriks.) |
| | P | Traded (The Kansas City Royals traded RHP David Sandlin to the Boston Red Sox.) From |
| | P | Traded (The Boston Red Sox traded RHP John Schreiber to the Kansas City Royals.) To |
| | P | Signed (The Boston Red Sox signed LHP Lucas Luetge to a minor league contract with an invitation to spring training.) |
| | SS | Non-roster Invitee (The Boston Red Sox invited INF Joe Dunand to spring training.) |
| | 3B | Non-roster Invitee (The Boston Red Sox invited INF Dalton Guthrie to spring training.) |
| | P | Non-roster Invitee (The Boston Red Sox invited RHP Melvin Adón to spring training.) |
| | P | Waived (The Boston Red Sox waived RHP Zack Weiss.) |
| | 3B | Signed (The Boston Red Sox signed INF Dalton Guthrie to a minor league contract.) |
| | P | Waived (The Boston Red Sox waived RHP Max Castillo.) |
| | 3B | Signed (The Boston Red Sox signed INF Dalton Guthrie to a minor league contract.) |
| | P | Signed (The Boston Red Sox signed RHP Michael Fulmer to a minor league contract.) |
| | P | Designated for Assignment (The Boston Red Sox designated RHP Max Castillo for assignment.) |
| | C | Traded (The New York Mets traded C Tyler Heineman to the Boston Red Sox.) From |
| | P | Designated for Assignment (The Boston Red Sox designated RHP Zack Weiss for assignment.) |
| | SS | Claimed on Unconditional Release Waivers (The Boston Red Sox claimed INF Romy González off waivers.) |
| | SS | Signed (The Boston Red Sox signed INF Joe Dunand to a minor league contract.) |
| | P | Non-roster Invitee (The Boston Red Sox invited RHP Alex Hoppe to spring training.) |
| | 2B | Non-roster Invitee (The Boston Red Sox invited INF Nick Yorke to spring training.) |
| | P | Non-roster Invitee (The Boston Red Sox invited RHP Andrew Politi to spring training.) |
| | P | Non-roster Invitee (The Boston Red Sox invited RHP Luis Guerrero to spring training.) |
| | 2B | Non-roster Invitee (The Boston Red Sox invited INF Chase Meidroth to spring training.) |
| | C | Non-roster Invitee (The Boston Red Sox invited C Nathan Hickey to spring training.) |
| | P | Non-roster Invitee (The Boston Red Sox invited RHP Justin Hagenman to spring training.) |
| | C | Non-roster Invitee (The Boston Red Sox invited C Stephen Scott to spring training.) |
| | SS | Non-roster Invitee (The Boston Red Sox invited INF Nick Sogard to spring training.) |
| | CF | Non-roster Invitee (The Boston Red Sox invited OF Corey Rosier to spring training.) |
| | P | Non-roster Invitee (The Boston Red Sox invited RHP Chase Shugart to spring training.) |
| | P | Signed (The Boston Red Sox signed RHP Melvin Adón to a minor league contract.) |
| | P | Released (The Boston Red Sox released RHP Mauricio Llovera.) |
| | P | Designated for Assignment (The Boston Red Sox designated RHP Mauricio Llovera for assignment.) |
| | P | Claimed on Unconditional Release Waivers (The Boston Red Sox claimed RHP Max Castillo off waivers from the Kansas City Royals.) |
| | P | Traded (The Boston Red Sox traded LHP Chris Sale to the Atlanta Braves.) To |
| | SS | Traded (The Atlanta Braves traded INF Vaughn Grissom to the Boston Red Sox.) From |
| | P | Signed (The Boston Red Sox signed RHP Lucas Giolito.) |
| | P | Traded (The Boston Red Sox traded RHP Victor Santos to the St. Louis Cardinals.) To |
| | RF | Traded (The St. Louis Cardinals traded OF Tyler O'Neill to the Boston Red Sox.) From |
| | P | Traded (The Boston Red Sox traded RHP Nick Robertson to the St. Louis Cardinals.) To |
| | P | Traded (The Boston Red Sox traded LHP Ryan Ammons to the New York Mets.) To |
| | C | Drafted Via Rule 5 (The Boston Red Sox selected C Mickey Gasper in the Rule 5 Draft.) |
| | P | Traded (The New York Mets traded RHP Justin Slaten to the Boston Red Sox.) From |
| | P | Traded (The New York Yankees traded RHP Nicholas Judice to the Boston Red Sox.) From |
| | LF | Traded (The Boston Red Sox traded OF Alex Verdugo to the New York Yankees.) To |
| | P | Traded (The New York Yankees traded RHP Greg Weissert to the Boston Red Sox.) From |
| | P | Traded (The New York Yankees traded RHP Richard Fitts to the Boston Red Sox.) From |
| | P | Signed (The Boston Red Sox signed LHP Jorge Benitez to a minor league contract.) |
| | P | Signed (The Boston Red Sox signed RHP Wyatt Mills to a minor league contract.) |
| | P | Traded (The Seattle Mariners traded RHP Isaiah Campbell to the Boston Red Sox.) From |
| | P | Released (The Boston Red Sox released RHP Wyatt Mills.) |
| | 3B | Traded (The Boston Red Sox traded INF Luis Urías to the Seattle Mariners.) To |
| | P | Signed (The Boston Red Sox signed RHP Luis Cabrera to a minor league contract.) |
| | P | Retired (RHP Joey Stock has voluntarily retired.) |
| | P | Signed (The Boston Red Sox signed RHP Luis Cabrera to a minor league contract.) |
| | C | Released (The Boston Red Sox released C Oscar Rangel.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox selected the contract of RHP Wikelman Gonzalez from the minors.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox selected the contract of RHP Luis Perales from the minors.) |
| | RF | Signed (The Boston Red Sox signed OF Mark Contreras to a minor league contract.) |
| | P | Declared Free Agency (RHP Aaron Perry elected free agency.) |
| | P | Declared Free Agency (LHP Oddanier Mosqueda elected free agency.) |
| | P | Declared Free Agency (LHP Brendan Nail elected free agency.) |
| | P | Declared Free Agency (LHP Rio Gomez elected free agency.) |
| | P | Declared Free Agency (RHP Sterling Sharp elected free agency.) |
| | P | Declared Free Agency (LHP Skylar Arias elected free agency.) |
| | CF | Declared Free Agency (OF Bradley Zimmer elected free agency.) |
| | 1B | Declared Free Agency (INF Tyreque Reed elected free agency.) |
| | P | Declared Free Agency (RHP Michael Gettys elected free agency.) |
| | RF | Declared Free Agency (OF Tyler Esplin elected free agency.) |
| | C | Declared Free Agency (C Ronaldo Hernández elected free agency.) |
| | RF | Declared Free Agency (OF Tyler Dearden elected free agency.) |
| | RF | Declared Free Agency (OF Narciso Crook declared free agency.) |
| | P | Declared Free Agency (RHP Justin Garza declared free agency.) |
| | P | Declared Free Agency (LHP Joely Rodríguez declared free agency.) |
| | P | Declared Free Agency (The Boston Red Sox LHP Joely Rodríguez declared free agency.) |
| | LF | Activated (The Boston Red Sox activated OF Jarren Duran.) |
| | P | Activated (The Boston Red Sox activated RHP Wyatt Mills.) |
| | P | Declared Free Agency (The Boston Red Sox RHP Corey Kluber declared free agency.) |
| | P | Activated (The Boston Red Sox activated LHP Joe Jacques.) |
| | P | Activated (The Boston Red Sox activated RHP Bryan Mata.) |
| | P | Activated (The Boston Red Sox activated LHP Brandon Walter.) |
| | SS | Activated (The Boston Red Sox activated INF David Hamilton.) |
| | P | Activated (The Boston Red Sox activated RHP Zack Weiss.) |
| | P | Activated (The Boston Red Sox activated RHP Chris Martin.) |
| | P | Activated (The Boston Red Sox activated RHP Logan Gillaspie.) |
| | 3B | Declared Free Agency (Boston Red Sox DH Justin Turner declared free agency.) |
| | 3B | Activated (The Boston Red Sox activated INF Triston Casas.) |
| | P | Activated (The Boston Red Sox activated LHP Joely Rodríguez.) |
| | 3B | Activated (The Boston Red Sox activated INF Luis Urías.) |
| | P | Declared Free Agency (Boston Red Sox LHP James Paxton declared free agency.) |
| | SS | Declared Free Agency (Boston Red Sox INF Adalberto Mondesi declared free agency.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP outright Justin Garza to the minors.) |
| | LF | Declared Free Agency (Boston Red Sox OF Adam Duvall declared free agency.) |
| | SS | Declared Free Agency (INF Yu Chang declared free agency.) |
| | P | Designated for Assignment (The Boston Red Sox designated RHP Kaleb Ort for assignment.) |
| | P | Activated (The Boston Red Sox activated RHP Kaleb Ort from the 60-day injured list.) |
| | P | Declared Free Agency (RHP Kyle Barraclough declared free agency.) |
| | C | Declared Free Agency (C Caleb Hamilton declared free agency.) |
| | 2B | Declared Free Agency (INF Christian Arroyo declared free agency.) |
| | P | Recalled From Minors Rehab (The Boston Red Sox recalled RHP Nick Robertson from the minors.) |
| | P | Placed on 15-Day IL (The Boston Red Sox placed RHP Chris Martin on the 15-day injured list.) |
| | P | Sent to Minors (The Boston Red Sox sent RHP Kyle Barraclough outright to the minors.) |
| | P | Designated for Assignment (The Boston Red Sox designated RHP Kyle Barraclough for assignment.) |
| | P | Sent to Minors (The Boston Red Sox optioned RHP Nick Robertson to the minors.) |
| | P | Activated (The Boston Red Sox activated RHP Zack Kelly from the 60-day injured list.) |
| | P | Sent to Minors (The Boston Red Sox optioned RHP Zack Weiss to the minors.) |
| | P | Activated (The Boston Red Sox activated RHP Kenley Jansen from the 7-day injured list.) |
| | 3B | Placed on 10-Day IL (The Boston Red Sox placed INF Luis Urías on the 10-day injured list.) |
| | 2B | Recalled From Minors Rehab (The Boston Red Sox recalled INF Enmanuel Valdez from the minors.) |