| Pitching | G | GS | W | L | SV | BS | HLD | CG | SHO | IP | H | R | ER | HR | BB | K | ERA | WHIP | BAA |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Totals | 74 | 30 | 29 | 8 | 29 | 83 | 3.35 | 1.32 | .248 | ||||||||||
| League Rank | 9 | 9 | 9 | T7 | 9 | 9 | 2 | 6 | 5 | ||||||||||
| Jon Lester | 3 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 20.0 | 19 | 8 | 7 | 1 | 2 | 16 | 3.15 | 1.05 | .241 |
| Felix Doubront | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.0 | 12 | 5 | 5 | 2 | 6 | 13 | 4.50 | 1.80 | .300 |
| John Lackey | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 8.2 | 14 | 7 | 7 | 1 | 2 | 11 | 7.27 | 1.85 | .350 |
| Clay Buchholz | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 7.0 | 2 | 0 | 0 | 0 | 3 | 8 | 0.00 | 0.71 | .091 |
| Junichi Tazawa | 4 | 0 | 2 | 1 | 0 | 2 | 1 | 0 | 0 | 4.1 | 5 | 3 | 3 | 2 | 2 | 6 | 6.23 | 1.62 | .278 |
| Clayton Mortensen | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.1 | 3 | 1 | 1 | 0 | 4 | 5 | 1.69 | 1.31 | .176 |
| Koji Uehara | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3.0 | 2 | 0 | 0 | 0 | 1 | 5 | 0.00 | 1.00 | .182 |
| Alfredo Aceves | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.2 | 3 | 3 | 3 | 1 | 2 | 5 | 7.36 | 1.36 | .214 |
| Ryan Dempster | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 6.0 | 4 | 1 | 1 | 1 | 3 | 4 | 1.50 | 1.17 | .200 |
| Andrew Miller | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.0 | 3 | 0 | 0 | 0 | 1 | 3 | 0.00 | 2.00 | .375 |
| Álex Wilson | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.0 | 2 | 1 | 1 | 0 | 1 | 2 | 9.00 | 3.00 | .400 |
| José De La Torre | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 2 | 0.00 | 0.00 | .000 |
| Joel Hanrahan | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.0 | 3 | 1 | 1 | 0 | 1 | 1 | 3.00 | 1.33 | .300 |
| Andrew Bailey | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 1 | 0.00 | 2.00 | .250 |
| Craig Breslow | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0.00 | 0.50 | .143 |