Buehrle, who is 14-7 with a 3.07 ERA this season, is 1-3 in his last four starts with a 4.65 ERA.
In a 7-5 loss to Texas on Tuesday, the left-hander gave up seven runs—four earned—and nine hits in seven innings.
“I made pitches in the first couple of innings and they hit them,” Buehrle said. “I guess you tip your hat to them.”
The White Sox have taken the first two games of the series, including a 9-1 win Friday.
Chicago took a 4-0 lead in the second, when A.J. Pierzynski had a run-scoring single and Uribe hit his 10th homer.
Willie Harris added a solo homer, his first of the season and just his fifth in his three-year career.
“I don’t hit homers too often,” Harris said. “I hardly know how it feels to have that trot. I tried to get around the bases and get back to the dugout.”
Harris is hitting .428 (9-for-21) since returning from a stint in the minors. He has four hits in his last two games, starting in place of infielder Tadahito Iguchi, who has missed time for personal reasons.
Detroit has lost seven of nine, falling to 63-69. Before Friday’s game, Tigers manager Alan Trammell talked about how his pitchers gave up six straight hits in the eighth inning of Thursday’s 12-3 loss to Chicago. Sean Douglass wasn’t much better, allowing five hits in the second inning.
“I’d say the pounding continued,” Trammell said. “Right now there are no answers. … We just can’t seem to get out of these jams without giving up something huge.”