Lopez, who lost a season-high three straight starts from June 26-July 5, has won consecutive outings since, including Friday’s 6-3 victory at Seattle. The right-hander, who leads the Orioles with nine wins, allowed three runs and eight hits over 5 1-3 innings, striking out three and walking one.
He’ll be shooting for his first three-start winning streak since June 10-21, when he was in the midst of a 5-0 stretch over six outings.
The Orioles took Monday’s series opener 3-2 and held the same lead in the bottom of the ninth on Tuesday before Minnesota staged a comeback against Baltimore closer B.J. Ryan.
The Twins closed within 12 games of the Chicago White Sox in the AL Central.
Baltimore’s Rafael Palmeiro had two hits Tuesday, raising his career total to 3,009 and moving into sole possession of 24th place, past Al Kaline, on the all-time list.