Palmeiro is one hit away from reaching the milestone after going 1-for-3 with a walk Thursday in a 5-3 win to open the series. He is also set to join Hall of Famers Hank Aaron, Willie Mays and Eddie Murray as the only players with 3,000 hits and 500 homers.
“You’re talking about some of the greatest guys of all time,” said Palmeiro, who has 566 career homers. “I’m not sure my name should be mentioned with those guys.”
The slugging first baseman is batting .309 (29-for-94) with seven homers and 18 RBIs over his last 26 games. He had homered in three straight contests before Thursday.
“Very impressive,” Orioles manager Lee Mazzilli said. “He’s been consistent his entire career. He’s stayed away from injuries.”
Palmeiro is hitting .300 (6-for-20) against Seattle starter Joel Pineiro. He has 225 career hits against Seattle with 51 homers—his most against any opponent.
Orioles starter Rodrigo Lopez seeks a second straight win after ending a personal three-game skid Sunday. Lopez gave up one run and three hits over eight innings in a 4-1 win over Boston.
He had been 0-3 with a 6.75 ERA over his previous three outings.
“This will give me more confidence, especially after those three bad outings,” Lopez said.
The 29-year-old right-hander is aiming for a second victory against Seattle this season after surrendering one run and five hits over eight innings in a 3-1 victory at Camden Yards on May 25. Lopez improved to 1-3 with a 4.76 ERA against the Mariners in five career appearances, including four starts.
Seattle manager Mike Hargrove is still searching for his first win against the team that fired him at the end of the 2003 season as the Mariners fell to 0-4 against the Orioles.
The Mariners managed a season-low two hits Thursday as their season-best four-game winning streak ended. Seattle has scored a total of eight runs in the losses to Baltimore.