After this series, the Reds, who have lost seven of their last eight, will play three at Arizona leading into the All-Star break.
Cincinnati has its worst record after 81 games since the 1934 Reds were 27-54 on their way to finishing 52-99.
“We’ve been looking for a clean game,” Reds interim manager Jerry Narron said. “We want a clean game, physically and mentally. You can’t make mistakes against a guy like Roger Clemens.”
Reds shortstop Felipe Lopez went 1-for-3 to raise his batting average to a team-high .321. Lopez was selected as Cincinnati’s lone All-Star representative on Sunday.
San Francisco will be starting a seven-game homestand after going 4-5 on its road trip.
Moises Alou went 1-for-4 with a double for the Giants. The veteran outfielder is San Francisco’s only All-Star.
“I feel honored,” Alou said. “It means a lot to me because this is my sixth time with five different teams. It means everywhere I go, I do a decent job.”
Alou’s father, Giants manager Felipe Alou, will be a coach on Tony La Russa’s NL staff.
“It will be cool to be in the same dugout with your Dad,” Moises Alou said. “I always appreciate playing for my Dad. It’s very special to go to the All-Star game with him.”