The Orioles lead the East by three games, thanks in no part to their 2-4 record in interleague play.
Baltimore’s offense was handcuffed by Pittsburgh’s Kip Wells as the Orioles lost their second straight game to the Pirates 6-1 on Wednesday.
The Orioles lost for the first time in nine road series this season (6-1-2), and in 14 road series (10-1-3) since losing two of three at Texas last Aug. 27-29.
“We’ve got to pick it up, we’ve got to go out and win, and there’s no question this team will do that, this team is like that,” Baltimore manager Lee Mazzilli said.
The streak of 13 consecutive road series without a loss was the majors’ longest since Atlanta had a 16-series run in 2002. The road streak was one short of Baltimore’s franchise best of 14 straight in 1983.
The Orioles hope to have second baseman Brian Roberts back in the lineup as they finish up a 13-game trip against the Reds.
Roberts has missed eight consecutive starts with a shoulder injury. He’s been used as a pinch-hitter over the last two games, a sign that he may be getting ready to rejoin Baltimore’s lineup.
Roberts doubled in his only at-bat Wednesday to raise his AL-leading batting average to .369. He leads Baltimore with 13 stolen bases and his 12 homers are second on the team to Miguel Tejada’s 17.
The Orioles take on a Cincinnati squad that is coming off a three-game sweep of the Tampa Bay Devil Rays.
Luke Hudson won his season debut with six solid innings, and the suddenly revived Reds routed the Devil Rays 14-5 on Thursday.
“We’ve got some confidence going,” Cincinnati first baseman Sean Casey said.
The Reds rallied from five-run deficits in each of the first two games of the series, the first time they’d done so since 1918.