San Diego has hit Wilson hard throughout his seven-year career. The 32-year-old right-hander is 1-6 with an 8.82 ERA in seven career starts against the Padres.
The veteran hurler could have used a break in the schedule to help him recover from a 13-6 loss to the Los Angeles Dodgers on Friday.
Wilson never got an out, giving up eight runs and five hits, including two homers. He walked one and hit two batters as his ERA jumped from 5.25 to 7.25.
“He had a hard time throwing strikes, and he was getting the ball up,” said Dodgers second baseman Jeff Kent, who homered off Wilson.
Padres outfielder Ryan Klesko has feasted on Wilson, hitting .538 (7-for-13) with five homers and seven RBIs against him.
Klesko has been stinging the ball of late, hitting .290 with five home runs over the last seven games.
Sean Casey drove in three runs with two doubles, and Cincinnati’s besieged bullpen ended a long stretch of miserable performances by preserving a 5-1 victory over San Diego on Tuesday.
“It was good to get some good things going and just to get a win, to tell you the truth,” said Casey after the Reds won for just the second time in 12 games.